Interpreting Molecular Readouts to Advance Cancer Medicine

18.6.2013

přednášková místnost Morávkova pavilonu / RECAMO

Masarykův onkologický ústav, Žlutý kopec 7, 656 53 Brno zobrazit na mapě / show map
Interpreting Molecular Readouts to Advance Cancer Medicine
  • Úterý 18. 6. 2013 v 14:30
  • seminář z cyklu "nádorová biologie"
  • přednášející: Dr. Ian Overton, University of Edinburgh

Research Areas: Integrative Network Biology 
We are applying data integration and network analyses to afford novel systems perspectives on gene function, particularly in cell invasiveness, migration and stem-like properties. The need for better diagnosis and treatment of common human diseases is a core motivator for this work.

Genetic control of cell behaviour is mediated through an intricate mesh of interconnected networks, not linear pathways. Many genes function in several cellular processes, and some can have seemingly opposite functions depending on context (e.g. to both promote and suppress cancer progression). Network properties can predict disease outcome, and contribute to incomplete penetrance of mutations (e.g. by thresholding stochastic fluctuations). Indeed, network biology is fundamental to understanding cell fate regulation and important for developing new clinical tools.

Přednášející / speakers

  • Dr. Ian Overton

    Dr. Ian Overton

    MRC Human Genetics Unit MRC IGMM, University of Edinburgh

POPLATEK / registration fee

Účast na semináři je díky podpoře z EU fondů pro projekt IntegRECAMO (OPVK CZ.1.07/2.3.00/20.0097) bezplatná.

Přihlášení

Přihlášení